Sarah Wayne Callies Reveals 'Rampant Misogyny' on 'Prison Break' Set

Callies, who starred as Sara Tancredi on the Fox drama, claims she experienced misogynistic behavior on set and had to talk her husband out of "hospitalizing somebody."

Sarah Wayne Callies Reveals 'Rampant Misogyny' on 'Prison Break' Set

Sarah Wayne Callies, who starred as Sara Tancredi in the hit Fox series "Prison Break," has opened up about her experiences on the show, alleging that she encountered "rampant misogyny" on set.

In a recent interview on the "Broad Ideas with Rachel Bilson & Olivia Allen" podcast, Callies candidly discussed her time on the drama series, which ran for five seasons from 2005 to 2017.

Sarah Wayne Callies Reveals 'Rampant Misogyny' on 'Prison Break' Set

Callies revealed that it was difficult to revisit that period of her life before starting a podcast with former co-star Paul Adelstein, in which they reflect on each "Prison Break" episode.

"I couldn't get beyond the parts that were toxic and painful," she explained.

Sarah Wayne Callies Reveals 'Rampant Misogyny' on 'Prison Break' Set

However, as she has moved into non-acting roles in the entertainment industry, Callies said she has developed a new perspective on her time on "Prison Break" and "The Walking Dead," where she played Lori Grimes for three seasons.

"I'm realizing I walk through doors that are open because of ‘Prison Break’ and because of ‘[The] Walking Dead.’ And so I'm now looking back at those shows with so much gratitude," she said.

Sarah Wayne Callies Reveals 'Rampant Misogyny' on 'Prison Break' Set

Despite this, Callies acknowledged the significant challenges she faced as the only woman on a predominantly male-dominated set and with producers who were also primarily men.

"There were two edges to that sword," she admitted. "I've had an actor on that show spit in my face. And I was like, ‘Holy s---.’ And like we will get there on the podcast. We will talk about it someday," she said, without naming her co-star.

Callies went on to describe the environment on set as so toxic that her husband wanted to intervene.

"There were things, like I would go home some nights and have to spend an hour talking my husband out of going to hospitalize somebody," she revealed.

While some of the male cast members were supportive, Callies said the sudden fame and attention she received from the show led to some "fools" who handled it poorly.

"Some of the guys were great, and some of them were totally gentlemen, but when you go from zero to 60, from nobody knows who I am to 'I'm on the carpet of award shows.' What's that thing they say that, like, ‘Any fool can handle adversity. You want to test a man’s medal, give him success.' Like, it was — and again, so much of it was also great and made lifelong friends and all the things. But I wasn't ready to look at it... for exactly that reason. Because I didn't want it to send me into a spiral of like, ‘What did I let them do to me? What did I let them say to me? What did I put up with? What did I not report?’"

A representative for Callies did not immediately respond to Fox News Digital's request for comment.