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**Title**: Oropouche Virus: A Traveler's Guide to Sloth Fever

The Oropouche virus, commonly known as sloth fever, is a mosquito-borne infection that has recently emerged as a concern for travelers returning from Cuba. With over 20 U.S. residents infected in recent months, it's essential to understand the symptoms, transmission, and prevention measures associated with this virus.

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**Article**:

The Oropouche virus (OROV), a member of the Simbu serogroup of viruses, was first isolated in 1959 in Trinidad and Tobago. It is primarily transmitted through the bite of infected midges, tiny biting flies known as Culicoides, which are found in humid tropical and subtropical regions of South and Central America, particularly in the Amazon rainforest.

**Symptoms**:

OROV infection typically causes a range of symptoms that appear 3-7 days after the bite of an infected midge. These symptoms can include:

* Fever

* Chills

* Headache

* Muscle aches

* Joint pain

* Fatigue

* Nausea

* Vomiting

* Diarrhea

* Rash

**Transmission**:

OROV is primarily transmitted through the bite of infected midges, which typically feed at dawn and dusk. The virus can also be transmitted through blood transfusions or organ transplants from infected individuals.

**Diagnosis**:

Diagnosis of OROV infection is based on clinical symptoms and laboratory testing. Blood tests can detect antibodies against the virus, confirming the diagnosis.

**Prevention**:

The most effective way to prevent OROV infection is to avoid midge bites. Travelers to endemic areas should take the following precautions:

* Wear long-sleeved shirts, pants, and socks while outdoors.

* Use insect repellent containing DEET or picaridin on exposed skin.

* Sleep under mosquito nets treated with insecticide.

* Keep doors and windows closed, especially at dawn and dusk.

**Treatment**:

There is no specific treatment for OROV infection. Treatment is supportive, aimed at relieving symptoms and preventing complications.

**Complications**:

In rare cases, OROV infection can lead to severe complications, such as:

* Meningoencephalitis (inflammation of the brain and spinal cord)

* Encephalitis (inflammation of the brain)

* Guillain-Barré syndrome (a neurological disorder affecting the nerves)

* Transverse myelitis (inflammation of the spinal cord)

**Outbreaks**:

Outbreaks of OROV infection have occurred sporadically in South and Central America, with the most recent major outbreak occurring in Peru in 2021. The recent infections in U.S. travelers returning from Cuba have highlighted the importance of awareness and prevention measures for individuals traveling to endemic regions.

**Conclusion**:

While OROV infection is typically not fatal, it can cause significant discomfort and even serious complications. Travelers to endemic areas should be aware of the symptoms and transmission of the virus and take appropriate precautions to avoid midge bites. By following these preventive measures, travelers can significantly reduce their risk of contracting sloth fever.